Gene description for SERPINC1 |
Gene name |
serpin family C member 1 |
Gene symbol |
SERPINC1 |
Other names/aliases |
AT3 AT3D ATIII ATIII-R2 ATIII-T1 ATIII-T2 THPH7 |
Species |
Homo sapiens |
Experiment description of studies that identified SERPINC1 in Glioblastoma cells |
1
|
Experiment ID | 722 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25802036
|
Organism | Homo sapiens |
Experiment description | Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. |
Authors | de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML. |
Journal name |
Int J Cancer
|
Publication year | 2015 |
Sample | Glioblastoma cells |
Sample name | U87.MG/EGFRvIII |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150064: EV-METRIC:0%, 0%, 29%
|
|
|
2
|
Experiment ID | 723 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25802036
|
Organism | Homo sapiens |
Experiment description | Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. |
Authors | de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML. |
Journal name |
Int J Cancer
|
Publication year | 2015 |
Sample | Glioblastoma cells |
Sample name | GS184 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150064: EV-METRIC:0%, 0%, 29%
|
|
|
3
|
Experiment ID | 1039 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | A172 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 1040 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | LN229 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 1041 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | U87MG |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 1042 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | U251 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 1043 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | T98G |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 1044 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | CCF-STTG1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 1242 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25261722
|
Organism | Homo sapiens |
Experiment description | Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. |
Authors | Kore RA, Abraham EC. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Glioblastoma cells |
Sample name | U373 cells treated with 10ng/ml of IL-1. |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140183: EV-METRIC:22%
|
|
|
10
|
Experiment ID | 1243 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25261722
|
Organism | Homo sapiens |
Experiment description | Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. |
Authors | Kore RA, Abraham EC. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Glioblastoma cells |
Sample name | U373 cells treated with 10ng/ml of TNF-. |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140183: EV-METRIC:22%
|
|
|